Re: [Az-Geocaching] Poison Oak/Ivy

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Author: Jim Stamm
Date:  
To: az-geocaching
Subject: Re: [Az-Geocaching] Poison Oak/Ivy
Trisha Radley wrote on 1/11/02 7:15 AM :

>Actually, that is a good example of how the body develops an allergic
>reaction/response (like beestings). The first time you are exposed, you have
>no allergic antigens to the offending substance, and your body develops
>these so that the next time you are exposed, your body has developed a
>"memory" in its immune system and attacks the substance...hence the allergic
>reaction. Not sure I explained that very well, but its early!


Good explanation, but it's a little more complicated than that. The
oils/chemicals from the poison ivy are not harmful to the skin, do not
cause any symptoms, and do not cause antibodies to be produced. The
invading chemical is "digested" (bad word), on the skin, and reacts with
the skin proteins. The resulting components are manifested as "foreign"
to the body's immune system. This usually takes hours, so there is time
to wash the junk off (if you know it is there.)

Now the immune system sends white blood cells to the "foreign" area,
where they end up attacking everything in the area. This is what causes
all the damage.

I don't remember the mechanism that explains "immunity," and why repeated
exposure results in greater damage.

-Jim